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Current

      Federal

1RO1HL58732-4 “Gap Junctions in vascular smooth muscle: Growth control”. (b) J.M. Burt, PI, (c) 7-97 to 7-04. (d) Annual direct costs $175,000 (e) Examination of the mechanistic basis for changes in gap junction function associated with cell cycle position and assessment of possible contribution of such changes to atherosclerosis.

T32 HL07249-21 " Graduate training in Physiology". (b) J.M. Burt, P.I., T. Secomb, Co-P.I. (c) 7-77 to 5-02. (d) Annual direct costs $182,592. (e) Training of 7 pre-doctoral and 4 post-doctoral candidates in each of the five-year award.

2R01HL049330-11Regulatory mechanisms of Cardiac Repolarization (subcontract from Colorado State University) (b) Michael Tamkun PI, J.M. Burt, subcontract P.I. (c) 5/2002 to 12/03. (d) Annual direct costs $32,000  (e) Influence of cholesterol depletion on Connexin localization and gap junction channel function in neonatal rat myocytes.

State and Private

American Heart Association -National (# 0050020N)  “Functional consequences of connexin interactions in blood vessels" (b) J.M. Burt, PI. (c) 1/00 to 12/02, extended to 12/03. (d) Annual direct costs $65,000. (e) Channels composed of Cx37 and Cx40 will be characterized. Communication in vessels isolated from knockout mice will be examined.