Research Interests

My research examines the voluntary and respiratory-related neuromuscular control of upper airway muscles.

Under my current� (K-23) award I proposed a series of experiments to be conducted in human subjects that will examine the modulation of human hypoglossal motor unit activities as a function of sleep and wakefulness, in response to respiratory-related sensory stimuli and during volitional movement. These experiments will provide insights into the nervous system (efferent and afferent components) control of the tongue muscles in healthy human subjects that will have implications for the neural control of movement in the broadest sense.

This research will provide the foundation for future studies of lingual motor control in upper airway muscles during more complex oromotor functions such as swallowing. The research extends and develops upon� my previous research� that focused on� the respiratory-related control of tongue muscle activities in the spontaneously breathing anesthetized rat, and will� lay the foundation� for an independent research program that combines behavioral and neurophysiological approaches to study lingual neuromuscular control in human and lower mammalian model systems.

Professional Memberships:

Society for Neuroscience, The American Physiological Society

Graduate Program Affiliations

Physiological Sciences

Publications

. Aug 2008. A Tasty Morsel: The Role of the Dorsal Vagal Complex in the Regulation of Food Intake and Swallowing. Am J Physiol Regul Integr Comp Physiol,2008 Aug 27;

Bailey, EF, Fridel, KW & Rice, A.D. Oct 2007. Sleep/wake firing patterns of human genioglossus motor units. J Neurophysiol. 2007 Oct,

Van Zutphen C Janssen P Hassan M Cabrera R Bailey EF Fregosi RF. Feb 2007. Regional velopharyngeal compliance in the rat: influence of tongue muscle contraction. NMR Biomed,2007 Feb 2;

Bailey EF, Rice AD, Fuglevand AJ. Oct 2006. Firing patterns of human genioglossus motor units during voluntary tongue movements. J Neurophysiol,2006 Oct 4;

Bailey EF Huang YH Fregosi RF. Jul 2006. THE ANATOMIC CONSEQUENCES OF INTRINSIC TONGUE MUSCLE ACTIVATION. J Appl Physiol,2006 Jul 6;

Bailey, EF, Fregosi, RF. May 2006. Modulation of Upper Airway Muscle Activities by Broncho-Pulmonary Afferents. J. Appl. Physiol., 101:609 - 617

John J, Bailey EF, Fregosi RF. Nov 2005. Respiratory-related Discharge of Genioglossus Muscle Motor Units. Am J Respir Crit Care Med, 172:1331-7

Bailey EF, Janssen PL, Fregosi RF. Jun 2005. PO2-dependent changes in intrinsic and extrinsic tongue muscle activities in the rat. Am J Respir Crit Care Med, 171:1403-7

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